Negligence – Causation. The first, second and fourth defendants' admitted failures, including to check the claimant's pedal pulses, had not caused her arm and leg amputations. However, the Queen's Bench Division held that the third defendant's admitted failure to refer the claimant for an urgent opinion from a vascular surgeon, who would have initiated coagulation so as to have avoided the upper limb ischaemia, had deprived her of that opportunity and awarded damages in the agreed sum of £150,000.